Description:

Nature's version of nanotechnology, chromosomes can "self-assemble" into some amazing structures!  The application of scanning force microscopy (SFM) has been used to provide high-resolution, three-dimensional images of uncoated and unstained human chromosomes in which surface features less than 50 nm have been resolved. Comparison of SFM images with light microscopy data has permitted identification of specific chromosomes, and images of a chromosome showing cytogenetic abnormalities have been detected.  This technique has applications in the imaging and analysis of chromosome structure.

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