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February 8, 2004
Source: Christian Schönenberger
References:
Description:
This image is of a fluorescence optical microscopy
image of YOYO labeled lamba DNA stretched using molecular combing.
The question of whether DNA is able to transport electrons has attracted much
interest, particularly as this ability may play a role as a repair mechanism
after radiation damage to the DNA helix. Experiments addressing DNA conductivity
have involved a large number of DNA strands doped with intercalated donor and
acceptor molecules, and the conductivity has been assessed from electron
transfer rates as a function of the distance between the donor and acceptor
sites. Experiments have taken direct measurements of electrical current as a
function of the potential applied across a few DNA molecules associated into
single ropes at least 600 nm long, which indicate efficient conduction through
the ropes. The resistivity values derived from these measurements are comparable
to those of conducting polymers, and indicate that DNA transports electrical
current as efficiently as a good semiconductor. This property, and the fact that
DNA molecules of specific composition ranging in length from just a few
nucleotides to chains several tens of micrometres long can be routinely
prepared, makes DNA ideally suited for the construction of mesoscopic electronic
devices.
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